• In recent years there has

  2019-04-17

  

  In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR

• African leaders are gathering in Addis

  2019-04-17

  

  African leaders are gathering in Addis Ababa, Ethiopia, this week for the first ever . The event brings together government officials, including minsters of finance, technical experts, and policymakers, with the goal of advancing the coverage of life-saving immunisations across the continent. In

• An interesting finding in the study of

  2019-04-17

  

  An interesting finding in the study of Ngabo and colleagues was that, after a huge drop in the number of admittances to hospital for rotavirus in 2013, there was no further fall the next year. As the researchers discuss, this finding might herald the beginning of a biennial pattern of rotavirus acti

• On Aug WHO quietly released

  2019-04-17

  

  On Aug 23, WHO quietly released a report that should be essential reading for all. Coming 15 years after the Abuja Declaration by African governments to commit to spending 15% of annual domestic budgets on health, concludes with a stark analysis: “For every US$100 that goes into state coffers in Afr

• There were differentially expressed genes identified from th

  2019-04-17

  

  There were 3151 differentially expressed genes identified from the transcriptome profiling data of 497 patients (Fig. 2). Among these differentially expressed genes, 2190 genes were found to be upregulated in the group with infiltrating lymphocytes ≥1%. As shown in Table 2, these genes were enriched

• br Methods We reviewed http

  2019-04-17

  

  Methods We reviewed http://www.canadiancancertrials.ca/ and http://www.ontario.canadiancancertrials.ca/ in order to identify ongoing bone oncology-related trials. We used the keywords: bone, bone metastasis, bone treatment, cancer therapy induced bone loss and bisphosphonates for searching. We al

• br Conflict of interest br

  2019-04-17

  

  Conflict of interest Introduction Patients with structural heart disease have an increased risk of sudden cardiac death, secondary to ventricular tachyarrhythmias in most cases. Implantable cardioverter–defibrillators (ICDs) are the treatment of choice. However, ventricular tachyarrhythmias ca

• br In Anand Bhopal s discussion March of

  2019-04-17

  

  In Anand Bhopal\'s discussion (March, 2015) of health inequalities, social determinants of health, and advocacy for social change in health care in the 21st century, we were disappointed to see little recognition of the branch of medicine that motilin receptor epitomises “societal doctors”: public

• br Discussion ATS is rare and there are few reports

  2019-04-16

  

  Discussion ATS is rare, and there are few reports of pregnant patients with this condition. Subbiah et al. [6] reported a case of pregnancy complicated with ATS in which ventricular ectopy was also decreased during pregnancy. The mechanism underlying the reduction of VA in pregnant patients with

• In this case report we

  2019-04-16

  

  In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation

• br Therapy for the CPVT br Conflict

  2019-04-16

  

  Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele

• The predicted mean time to attaining the

  2019-04-16

  

  The predicted mean time to attaining the maximal indirect impact is relevant when considering adult vaccination with PCV. Most developed countries do not recommend PCV in adults, believing that with the high coverage in the infant programme, adult disease will (eventually) decline. The US vaccine de

• On the basis of this mechanism the

  2019-04-16

  

  On the basis of this mechanism, the prolonged RR interval with the patient\'s symptoms was likely a reflection of the progression of the AV block with an underlying first-degree AV block. Despite a first-degree AV block (420ms) during the short RP rhythm, a short PR interval (160ms) was observed wit

• br Case report An year old man with

  2019-04-16

  

  Case report An 81-year-old man with ischemic cardiomyopathy underwent ICD myd88 inhibitor for primary prevention in February 2007. The patient had never experienced spontaneous VF. A Riata™ 1570 dual-coiled lead (St. Jude Medical, Sylmar, CA) was passed through the left cephalic vein and connect

• br No por sobradamente conocido puede

  2019-04-16

  

  No por sobradamente conocido puede obviarse un breve esbozo del caso Jusep Torres Campalans, siquiera sea tachykinin receptor modo de comienzo y como marco general. En medio de una gran expectación generada por el diario Excélsior, que despacha siete artículos anticipatorios en apenas un mes, el 2

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