• One week after the CCRT she was brought to

  2019-04-18

  

  One week after the CCRT, she was brought to our emergency department due to fever, severe general weakness, and severe oral pain. Her Sicca syndrome-related xerostomia had worsened due to radiotherapy and was complicated with severe stomatitis, which made oral intake difficult. She took traditional

• It is established that hypoxia can induce autophagy We

  2019-04-18

  

  It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 order fexofenadine hydrochloride after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue

• br Contributors br Funding br Conflict of

  2019-04-18

  

  Contributors Funding Conflict of interest Patient consent Ethics approval Acknowledgment Introduction Perforation of a cardiac chamber has been reported as a relatively rare complication of pacemaker implantation; in particular, attachment of the active-fixation atrial lead to t

• br Raising taxes on tobacco is

  2019-04-18

  

  Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2

• neuropeptide receptors Having to seek various approvals with

  2019-04-18

  

  Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen

• La incorporaci n de los atributos

  2019-04-18

  

  La incorporación de los atributos culturales asociados p97 la población indígena en las instituciones religiosas, entre ellos el idioma, fue de vital importancia en el desarrollo, especialmente dinámico a partir de los años cincuenta del siglo xx en distintas instituciones de inspiración evangélica

• br CONSIDERACIONES FINALES Como se infiere de los ejemplos r

  2019-04-18

  

  CONSIDERACIONES FINALES Como se infiere de los ejemplos revisados en el apartado anterior, podríamos decir que esta suerte de homenaje póstumo concretado en las notas necrológicas de la RF está destinado uncouplers of oxidative phosphorylation figuras intelectuales que sintonizan con la orientaci

• br Materials and methods br Results We observed patterns of

  2019-04-17

  

  Materials and methods Results We observed 3 patterns of response to PHP. Pattern 1, observed in 56% of patients (nos. 4, 6, 7, 8, and 9), was characterized by S–A and V–A intervals in the septal region that were identical whether HB was captured or not, along with an unchanged atrial activatio

• En el Estudio preliminar el lector encontrar

  2019-04-17

  

  En el “Estudio preliminar”, el lector encontrará un magnífico marco de referencia para ubicar con precisión la obra. Contra una vieja mala costumbre de la crítica mexicañista más convencional de repetir una y otra vez los juicios críticos de los grandes maestros, Belem Clark de Lara teje una trama m

• However transparency has declined rather

  2019-04-17

  

  However, transparency has declined rather than improved. A recent analysis in the ranked PEPFAR as very poor—50th of 67 aid agencies worldwide. The report noted that, “PEPFAR does not disclose information on contracts to prime partners and sub-partners in a machine-readable and open format consiste

• br It s that time of year again

  2019-04-17

  

  It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations. A

• In recent years there has

  2019-04-17

  

  In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR

• African leaders are gathering in Addis

  2019-04-17

  

  African leaders are gathering in Addis Ababa, Ethiopia, this week for the first ever . The event brings together government officials, including minsters of finance, technical experts, and policymakers, with the goal of advancing the coverage of life-saving immunisations across the continent. In

• An interesting finding in the study of

  2019-04-17

  

  An interesting finding in the study of Ngabo and colleagues was that, after a huge drop in the number of admittances to hospital for rotavirus in 2013, there was no further fall the next year. As the researchers discuss, this finding might herald the beginning of a biennial pattern of rotavirus acti

• On Aug WHO quietly released

  2019-04-17

  

  On Aug 23, WHO quietly released a report that should be essential reading for all. Coming 15 years after the Abuja Declaration by African governments to commit to spending 15% of annual domestic budgets on health, concludes with a stark analysis: “For every US$100 that goes into state coffers in Afr

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