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In MM the optimal sequence or combination of the different
2019-06-10
In MM, the optimal sequence or combination of the different therapeutic regimens available remains unclear and information is needed on the efficacy of each treatment after various prior therapies. Although a substantial number of different regimens and schedules were used for the treatment of first
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Introduction Despite advances in the treatment of early stag
2019-06-10
Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant g-quadruplex [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is multidiscip
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br Conclusions br Limitation br Acknowledgments This researc
2019-06-10
Conclusions Limitation Acknowledgments This research was supported in part by the China Postdoctoral Science Foundation (Nos. 2013M542478 and 2015T81139), a Grant (no. 2014FB059) from the Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical Uni
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br Conflict of interest br Introduction For decades
2019-06-06
Conflict of interest Introduction For decades, cancer has been the leading cause of death in Taiwan. In 2012, esophageal cancer was the eighth most common cancer globally, with 456,000 new cases presenting that year. Esophageal cancer caused approximately 400,000 deaths in 2012, up from 345,00
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A review by Keung and
2019-06-06
A 2002 review by Keung and colleagues summarized cases of hematologic malignancy in patients with KS reported between 1961 and 2002 [3]. They described 12 cases of AML in KS in the literature during that time period. Based on the review of the current literature, we found approximately 10 additional
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ZIKV is a flavivirus related to dengue virus DENV
2019-06-06
ZIKV is a flavivirus related to dengue virus (DENV) and historically has been transmitted by the same mosquito species, (). There is no available treatment or vaccine so disease control is limited to the management of mosquitoes which currently relies on either insecticides or the destruction of lar
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Sephin1 br Among the most important
2019-06-06
Among the most important findings to have emerged from the massive 2013–16 outbreak of Ebola virus disease in west Africa is the delayed clearance of virus from the semen of men who survived the disease and the consequent risk of sexual transmission of the virus, although this seems to be rare. In
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A second methodological issue concerns the accuracy
2019-06-06
A second methodological issue concerns the accuracy of the exposure measurement. Without accurate measurement, different methods for calculating attributable risk that are equivalent in theory are not guaranteed to give compatible results in practice. Previous experience with carcinogenic infection
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br Conflict of interest br Ethics br
2019-06-06
Conflict of interest Ethics Acknowledgment This study was supported by TRF Grants from the Senior Research Scholar Grant, Thailand Research Fund Grant number RTA5580004, and the Higher Education Research Promotion and National Research University Project of Thailand, Office of the Higher Ed
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Sultan et al retrospectively searched
2019-06-06
Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop
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Introduction Several types of cancers including those origin
2019-06-06
Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s
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M s all de la tiran
2019-06-06
Más allá de la tiranía de las vanidades, existían sólidos argumentos que justificaban el alejamiento de Paz con respecto poly ic la poesía y la persona de Neruda. Con leve antelación a sus contemporáneos chilenos, Octavio Paz resaltaba dos principales defectos en la producción poética de Neruda: la
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Si bien esta amerita un an lisis detallado
2019-06-06
Si bien esta amerita un análisis detallado, me detendré en algunas cuestiones que considero clave para entender el modo en cómo resuelve Vigil la integración del pasado colonial. En primer lugar, aparece ya una clara intención de situar imidazoline éste como los orígenes de lo que será la nación me
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br The Medical Education Partnership
2019-06-06
The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource needs in sub-Saharan Africa. MEPI allows African institutions that Tediz
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ptio Supplier The data also revealed notable differences in
2019-06-05
The data also revealed notable differences in practice patterns across the countries. In France, Italy, Spain and the UK, patients were most likely to have multiple disseminated sites of metastases at the time of initial bone ptio Supplier detection; however, patients in Germany were most likely to
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